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March 11 – April 18, 2002 What follows is my entire correspondence with Robert Cohen. It’s copied here verbatim, except for footers, full headers, and repetitively quoted messages. Because of an unnoticed clock error on my computer, the dates for several of the first messages appear out of sequence. But the messages are displayed in the order in which they were sent and received. (NOTE: A glitch has caused the lines to become double-spaced.) Syd Baumel
From: "Syd Baumel" <baumel@mts.net> To: <notmilkman@notmilk.com> Subject: About Hjartaker et al. Date: Mon, 11 Mar 2002 21:47:58 -0600 Dear Robert, I'm doing a report for aquarianonline.com on the controversy over milk. It's a larger version of a print article I wrote for plant-based, an outreach publication within The Aquarian from the Winnipeg Vegetarian Association, of which I'm a member (I'm a vegan). I'm also editor of The Aquarian. I'm aware of the controversy over your critique of Lynette [sic: Anette] Hjartaker et al.'s study suggesting milk protects against breast cancer. I've read Stephen Walsh's open letter and corresponded with him and with Dr. Hjartaker. I've also read the original paper. I'd like to understand why you made the contested interpretations so I can report on this issue fairly and accurately. May I ask you a few questions? I'll quote from your critique and preface my queries with ****. You wrote: Here are my criticisms of the "study." 1) 317 of the 48,844 women in the study got breast cancer (six tenths of one percent), but the study actually began with 57,664 women. Why were the data from 8820 women eliminated? It turns out that 986 of those women had cancer too (11%). What does that indicate regarding the entire study? ****Do you have any reason to reject Hjartaker's explanation (and Walsh's and my own impression as a health/medicine writer) that this was a result of standard procedure in a prospective cohort study. Here's what she wrote to me: It is correct that we excluded 986 women with cancer prior to the study onset. This is in line with the study design we used, that is, a cohort study. An inclusion criteria for participating in this kind of study is that the subject has to be free from the disease under investigation when included. That is, cohort studies always only include subjects that are free from the disease under investigation. In our situation, free from cancer. Including only subjects free from the disease under investigation gives cohort studies a stronger design than for instance case-control studies (which include both diseased and healthy subjects). One reason is that subjects who have got a disease often will report differently on various exposure variables (such as dietary habits) than subjects who have not got the disease. Diseased subjects are more likely to thoroughly examined their dietary habits etc. You can read about this in e.g. Rothman and Greenlands's book 'Moderne epidemiology'. ****If you still think there is something fishy about this, can you answer your own question: "What does that indicate regarding the entire study?" 3) TABLE 3 reveals the incidence rate ratios of breast cancer according to milk consumption as a child and as an adult. Based upon population statistics supplied by the authors, the expectatiopn of breast cancers for low milk consuming females was 156 cases out of 311. The actual number of cases was only 42. ****Going by the case data you give, you must have meant the age-adjusted model in Table 4. I can't tell from Hjartaker's paper which "population statistics supplied by the authors" you used to arrive at your expected case values, which seem radically inconsistent with the milk consumption figures in Table 1. Could you provide these to me? Here's what Hjartaker wrote when I asked her to comment on your figures: It's right [i.e. Walsh's analysis], - Cohen must have made a gross and arbitrary exaggeration of the proportion of women in the low milk intake group. The analyses we applied was Cox regression. In these analyses you don't use number of persons in the different categories, but rather person-years, and calculate RATE RATIOS. In that case, one takes the follow-up time into account as well as the number of people included, and by that calculates 'number of person years'. Secondly, we adjust for several variables as described in our analyses. Taking both the follow-up time and the adjustments into account one will not get exactly the same figures as Walsh has reached, but for this purpose the figures should be close enough. ____ Thanks for your consideration. Syd Baumel Editor, The Aquarian www.aquarianonline.com _______________________________________________________ Subject: About Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Thu, 14 Mar 2002 04:31:29 -0500 To: "baumel@mts.net" <baumel@mts.net> Dear Syd, Please obtain an ORIGINAL copy of the study, and I will guide you through it. You will note that the levels of milk consumption change within the study (low, medium, high doses change from 1-3 to 1-5, for example). This is an extremely biased and poorly designed study, and I will be happy to be your guide. When you are ready to discuss same, call my office at 201-871-5871. Regards, Robert ________________________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: About Hjartaker et al. Date: Wed, 13 Mar 2002 13:54:00 -0600 Hi Robert, I do have a copy of the original paper (as I wrote), i.e. one I photocopied at the local medical library and have read from start to finish (well, minus some of the really boring parts). Would it be asking too much, as a favour to an overworked writer with a less than iron-clad grasp of Cox proportional hazards regression analyses, if you could just spell out in writing the details of your critique? I have years of experience reviewing medical literature, so if a scientist can understand your critique, so probably can I, with a little homework, perhaps. If not, I'll run it by Walsh, Hjartaker, or some more neutral third party. Indeed, even if I do follow it perfectly I would like to run it by them for comment and return those comments to you for review or rebuttal. I gather you relish the opportunity to debate milk-related issues, and this would be a good way to accomplish that. Also, there would be no danger of anyone being misquoted or taken out of context. Even better (I'm on a roll here), how about if we cc the correspondence to Walsh, Hjartaker, and anyone else you might like to include. I suspect Walsh would welcome the opportunity to cc it to the IVU-SCI newsgroup as well, and it could also be "simulcast" to your newsgroup, if you like. Let's open this issue up to public discussion and review. What do you think? Thanks, Syd _______________________________________________________ Subject: About Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Thu, 14 Mar 2002 16:44:13 -0500 To: "baumel@mts.net" <baumel@mts.net> CC: "dorietz@awod.com" <dorietz@awod.com> baumel@mts.net wrote {I do have a copy of the original paper (as I wrote), i.e. one I photocopied at the local medical library and have read from start to finish (well, minus some of the really boring parts). Would it be asking too much, as a favour to an overworked writer with a less than iron-clad grasp of Cox proportional hazards regression analyses, if you could just spell out in writing the details of your critique?} Huh? I've already done that. LOL Yes, it would be a bit too much. I am on the way to Toronto. Packing my van. Sorry you did not take advantage of my phone call offer. Perhaps some other time. {I have years of experience reviewing medical literature, so if a scientist can understand your critique, so probably can I, with a little homework, perhaps. If not, I'll run it by Walsh, Hjartaker, or some more neutral third party.} Indeed, even if I do follow it perfectly I would like to run it by them for comment and return those comments to you for review or rebuttal.} Perhaps you are not familiar with my experiences with Walsh, but I will have nothing to do with him. I am not interested in conversing with him. Nor do I have any interest in anything he has to say. End of subject. {Also, there would be no danger of anyone being misquoted or taken out of context. Even better (I'm on a roll here), how about if we cc the correspondence to Walsh, Hjartaker, and anyone else you might like to include. I suspect Walsh would welcome the opportunity to cc it to the IVU-SCI newsgroup as well, and it could also be "simulcast" to your newsgroup, if you like. Let's open this issue up to public discussion and review. What do you think?} What do I think, Sid? LOL Judging by the past, I think that you may very well cut and paste my comments together, just as others have done during this recent controversy. You are invited to post detailed comments to my guestbook. So is Dr. Hjartaker. Mr. Walsh may take his forum anywhere else he wishes, but I will have nothing to do with him. Robert Cohen http://www.notmilk.com _______________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: About Hjartaker et al. Date: Sun, 24 Mar 2002 00:52:02 -0600 Robert, May I call you then to discuss the Hjartaker paper? I'd like to record the interview for accuracy (as I always do), if you have no objections. Would an afternoon or evening call (CST) work for you? Syd _______________________________________________ Subject: About Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Mon, 25 Mar 2002 09:38:28 -0500 To: "baumel@mts.net" <baumel@mts.net> Robert, May I call you then to discuss the Hjartaker paper? I'd like to record the interview for accuracy (as I always do), if you have no objections. Would an afternoon or evening call (CST) work for you? Dear Syd, I look forward to it! Please call Lisa at 201-871-5871. She schedules all interviews for me. Save me a bit of time please, as I place about four cubic feet of papers into storage each week, and FAX the original Hjartaker study to my office. FAX: 201-871-9304 Regards, Robert Cohen ________________________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: About Hjartaker et al. Date: Sun, 24 Mar 2002 12:26:11 -0600 Robert, Thanks. Could I ask you to dig up that paper yourself? I'd love to accomodate you, but my photocopy is so reduced I have to squint to read it and a fax will be even less legible - plus I don't have a fax machine anyway! (just my computer, which requires pre-scanning), so I'd have to "outsource" to fax it to you. If your copy has really gone hiding, let me know and I'll see what I can do. Please let me know either way so I can schedule that call. Regards, Syd ___________________________________________________ Subject: About Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Mon, 25 Mar 2002 14:43:09 -0500 To: "baumel@mts.net" <baumel@mts.net> Robert, Thanks. Could I ask you to dig up that paper yourself? You could, but it will take a few weeks. I am on tour, and last week I transported about 150 boxes worth of "stuff" into a monthly storage shed. I should have a better storage system, but I do not. Why not find a good copy machine? My snail mail: Robert Cohen 560 Oradell Avenue Oradell, NJ 07649 _____________________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: About Hjartaker et al. Date: Sun, 24 Mar 2002 16:31:53 -0600 Robert, I'm trying to meet a commitment to complete and publish the report online by the end of the month. So it would be highly desirable if I could talk to you this week. How about if I scan and email you the study as printable (or viewable) gifs, jpegs, or tifs (what's your preference? gifs seem the easiest for me)? The file size (complete) could be as low as 1 Mb. Syd ________________________________________ Subject: About Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Mon, 25 Mar 2002 18:02:09 -0500 To: "baumel@mts.net" <baumel@mts.net> I'm trying to meet a commitment to complete and publish the report online by the end of the month. So it would be highly desirable if I could talk to you this week. That is not possible. I'm trying to meet a commitment to complete and publish the report online by the end of the month. I have three more hours of radio interviews today. I have a few dozen interviews during the next week, three speaking engagements, a number of meetings in New York city. I will be in Los Angeles from Wednesday until Friday. I have a few TV shows to do, and am doing an informercial. I also have an intense writing schedule. I receive over 2000 email letters per day, with dozens of daily requests for interviews. I have advised that you speak with Lisa so that we can work out a time. to schedule your interview. I do NOT open up files on the Internet. I make no exceptions. My FAX number is 201-871-9304. Regards, Robert Cohen _______________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Hjartaker et al. Date: Tue, 16 Apr 2002 22:36:58 -0500 Hi Robert, I thought I'd run this by you in advance of our scheduled conversation next Tuesday. It's from a draft of my article-in-progress on the conflict over the Hjartaker study (which I faxed to your office shortly after your last email; your secretary confirmed receipt when we scheduled the interview). This part focuses on the two major areas of disagreement between you and Walsh and Hjartaker. I welcome your comments. Regards, Syd Baumel www.aquarianonline.com ____ Based on what he claimed to be a truly critical analysis of the original paper, Cohen charged the authors with two particularly grievous crimes of deceit. Insinuating shady data manipulation, Cohen wrote: "317 of the 48,844 women in the study got breast cancer (six tenths of one percent), but the study actually began with 57,664 women. Why were the data from 8820 women eliminated? It turns out that 986 of those women had cancer too (11%). What does that indicate regarding the entire study?" In answer to Cohen's finger-pointing, Walsh explained that the 986 women, all of whom were found to have a prior diagnosis of cancer at the time they enrolled in the study, were automatically excluded by virtue of standard, sound study design. The paper, which I have also read, detailed the equally innocuous reasons for excluding the remainder of the 8820 women. Most, for example, had simply not been asked to fill out a dietary questionnaire when they were entered into the study. As Hjartåker (whom I asked for comment) explains: "Cohort studies [studies that follow a clearly defined group of people over time] always only include subjects that are free from the disease under investigation. In our situation, free from cancer." Indeed, the study was essentially a fishing expedition to take the measure (dietary and otherwise) of a very large, randomly selected "cohort" of cancer-free premenopausal women at its inception in 1991 and 1992, and, as the years go by, to see how those measurements relate to who gets cancer and who doesn't. . . . . . When I emailed Hjartåker for her two cents worth, she agreed that "Cohen must have made a gross and arbitrary exaggeration of the proportion of women in the low milk intake group." Her group had used "Cox regression," she explained. "In these analyses you don't use number of persons in the different categories, but rather person-years, and calculate RATE RATIOS. . . .Taking both the follow-up time and the adjustments into account one will not get exactly the same figures as Walsh has reached," Hjartåker wrote, "but for this purpose the figures should be close enough." I wanted to do better than "close enough," so I asked Hjartåker if she could provide the details of how she and her associates had converted the published figures of four discrete categories of milk intake into the three categories used in the combined analysis. "I hope this doesn't seem like an 'interrogation,'" I wrote. "My purpose is to present the truth as transparently and unambiguously as possible." That was March 17, and while I was waiting for Dr. Hjartåker's reply, Walsh steered me to a few lines in the "methods" section I had bumblingly overlooked wherein Hjartåker and company do explain their formula. It is a bit of a braintwister, which might explain Cohen's incomprehensible interpretation. To quote from the paper: "The combined effect of childhood and adult milk consumption was examined by constructing a 3-level variable: 'low consumption,' defined as no milk consumption on at least one of the occasions and not more than next-lowest consumption on the other occasion; 'high consumption,' defined as the highest milk consumption on at least 1 of the occasions and not less than the next-highest consumption on the other occasions and 'moderate consumption,' defined as all the other combinations." Judging by the raw data in the paper alone, this little algorithm meant that the low group would have contained somewhere between 6.6% and 16.1% of the women, the high group between 1.9% and 12.3%, and the moderate group everyone else. Taking those ranges and comparing them to the relative risks that the researchers published, but not knowing about the inclusion of person-years in the calculations, Walsh deduced that low, moderate, and high had been 11%, 82%, and 7%, respectively. When Hjartaker later responded to my query with the raw "person years" in each group (low: 32 280; Moderate: 242 209; High: 22 271) in the age-adjusted analysis, they almost perfectly matched Walsh's estimate: 10.9%, 81.6%, and 7.5%. Most importantly, they weren't even remotely similar to the figures Cohen had invoked to arrive at his damning conclusions of fraud and incompetence. When I used these figures together with the published numbers of breast cancer cases (adjusted for age) in the three different groups to calculate the RRs (relative risks), I obtained the following results: Low milk consumption: 42 cases (42/32,280 person years = 0.130%) Moderate milk consumption: 254 cases (254/242,209 = 0.1049%) High milk consumption: 15 cases (15/22,271 = 0.0674%) Setting "Low" (0.130%) as RR = 1, as Hjartaker et al. did, yielded the following RRs for the other two groups: Moderate: 0.1049/0.1300 = 0.807 (Hjartaker et al.'s published figure: 0.81) High: 0.0674/0.1300 = 0.518 (Hjartaker et al.: 0.54) That's close enough for me, and if Robert Cohen or anyone else can still find fault with Hjartaker et al.'s data, I'm all ears. __________________________________________________ Subject: Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Wed, 17 Apr 2002 10:46:08 -0400 To: "baumel@mts.net" <baumel@mts.net> CC: "notmilk@earthlink.net" <notmilk@earthlink.net> In any study, criteria must remain standardized. Let me ask you this. In th AH study, please define: CHILDREN Low milk consumption - How much? Medium consumption - How much? High consumption - How much? ADULT Low milk consumption - How much? Medium consumption - How much? High consumption - How much? Thanks, Robert ________________________________________________ Subject: Hjartaker et al. From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Wed, 17 Apr 2002 11:09:28 -0400 To: "baumel@mts.net" <baumel@mts.net> CC: "notmilk@earthlink.net" <notmilk@earthlink.net> I thought I'd run this by you in advance of our scheduled conversation next Tuesday. I welcome your comments. Dear Syd, Is the purpose of scientific pursuit the discovery of TRUTH, or the manipulation of data. One can make an argument that an individual drowned in a stream with the average depth pf four inches. The stream could have an average depth of one inch for 100 square miles, but that lethal 10 squar foot section could be the key event. That which you have written contains biased language. You wrote: <<Insinuating shady data manipulation, Cohen wrote>> Such language not only biases your potential readers, but shows me your intent. You continue: <<In answer to Cohen's finger-pointing>> So, up to this point you have me acting shady, insinuating, and finger pointing. You then have my critic say: <<986 women, all of whom were found to have a prior diagnosis of cancer at the time they enrolled in the study, were auto= matically excluded by virtue of standard, sound study design.>> This is NOT standard study design. Again, your bias. If the purpose of the study is to determine how many people develop cancer as a result of childhood habits, one must include the entire population from childhood to adulthood. By eliminating those with cancer, one biases the study. You write: The paper, which I have also read, detailed the equally innocuous reasons for excluding the remainder of the 8820 women. Most, for example, had simply not been asked to fill out a dietary questionnaire when they were entered into the study.>> "Simply not been asked to fill out a dietary questionairre??????" Why not? More experimental bias, that's why. <<As Hjart=E5ker (whom I asked for comment) explains: "Cohort studies [studies that follow a clearly defined group of people over time] always only include subjects that are free from the disease under investigation. In our situation, free from cancer.">> That reveals the flaw. Hjartaker clearly set up the parameter of the study. She defined the terms. Does milk consumption as a child cause cancer as an adult? This question cannot be answered honestly by eliminating those who got cancer. cancer? <<Indeed, the study was essentially a fishing expedition to take the measure (dietary and otherwise) of a very large, randomly selected "cohort" of cancer-free premenopausal women at its inception in 1991 and 1992, and, as the years go by, to see how those measurements relate to who gets cancer and who doesn't.>> Indeed????? Essentially??? They were not randomly selected if a large part of the population was excused for having cancer which they may have gotten as a result of childhood milk consumption. <<When I emailed Hjart=E5ker for her two cents worth, she agreed that "Cohen must have made a gross and arbitrary exaggeration of the proportion of women in the low milk intake group.">> ASK HER HOW SHE DETERMINED LOW, MEDIUM, AND HIGH CONSUMPTION. The numbers are different for kids and adults. How did she draw her arbitrary lines. Is low consumption 1-2 glasses or less than one, etc. <<Walsh steered me to a few lines in the "methods" section I had bumblingly overlooked wherein Hjart=E5ker and company do explain their formula. It is a bit of a braintwister, which might explain Cohen's incomprehensible interpretation. To quote from the paper:>> Incomprehensible intermpretation? Perhaps we should not do the interview, and have you just write whatver you will. ____________________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: Hjartaker et al. Date: Wed, 17 Apr 2002 14:48:08 -0500 ----- Original Message ----- From: <i4crob@earthlink.net> To: <baumel@mts.net> Cc: <notmilk@earthlink.net> Sent: Wednesday, April 17, 2002 10:09 AM Subject: Hjartaker et al.
I thought I'd run this by you in advance of our scheduled conversation next Tuesday. I welcome your comments. Dear Syd, Is the purpose of scientific pursuit the discovery of TRUTH, or the manipulation of data. One can make an argument that an individual drowned in a stream with the average depth pf four inches. The stream could have an average depth of one inch for 100 square miles, but that lethal 10 squar foot section could be the key event. That which you have written contains biased language. You wrote: <<Insinuating shady data manipulation, Cohen wrote>> Such language not only biases your potential readers, but shows me your intent.
***Robert, those judgemental words (far, far less judgemental than your published words with regard to Hjartaker et al.) represent how I regard your position based on my current knowledge. I'd be more than happy to sing your praises instead if our further communications give me sound reasons to. Please remember, this is just a draft of my article. I could have - and had wanted to, because of scheduling commitments - published it weeks ago after you refused to discuss this subject by email. But I decided I had a responsibility not to go to print until I'd given you every reasonable opportunity to explain your views to me in the manner of your choosing. I even went to considerable trouble to scan, format, and fax the original paper to you to spare you the trouble and delay of having to retrieve your copy, as you wrote to me, from boxes upon boxes of stored and uncatalogued material. ***Also, let me ask you: were you NOT, then, insinuating the researchers had manipulated data? You'd already described this as "the fraudulent study of the century" and primed your readers expectations by writing: "Today I present you with an amazing story of scientific fraud and deceit. This lie made every major American newspaper and television news program." How else did you want readers to interpret your reference to all those excluded cancer cases? I would really like to know if you had something else in mind, because I'll be happy to quote you on that. You continue: <<In answer to Cohen's finger-pointing>> So, up to this point you have me acting shady, insinuating, and finger pointing. You then have my critic say: ***Again, if you deserve credit for exposing scientific fraud rather than criticism for an unfounded attack on people conducting proper scientific research, I will very happily report that. Just convince me. I take my responsibilities as a journalist very seriously. <<986 women, all of whom were found to have a prior diagnosis of cancer at the time they enrolled in the study, were automatically excluded by virtue of standard, sound study design.>> This is NOT standard study design. Again, your bias. If the purpose of the study is to determine how many people develop cancer as a result of childhood habits, one must include the entire population from childhood to adulthood. By eliminating those with cancer, one biases the study. ****If the reseachers had set out to answer that question via case-control methodology, you'd have a point. But they chose to try and answer it via what is generally, if not universally, accepted by scientists as a less error-prone design: a prospective cohort study. For that reason, those women were not even enrolled in the study (i.e. they failed to meet the a priori inclusion criteria), let alone given dietary questionnaires and then - as I believe most readers who trust your critique would conclude - swept under the rug to bury some anti-milk effect. Again, if your rhetorical intent was otherwise, please say exactly what you want(ed) your readers to think. You write: The paper, which I have also read, detailed the equally innocuous reasons for excluding the remainder of the 8820 women. Most, for example, had simply not been asked to fill out a dietary questionnaire when they were entered into the study.>> "Simply not been asked to fill out a dietary questionairre??????" Why not? More experimental bias,
that's why.
****Bias in which direction? Anti-milk or pro-milk? According to the paper (p. 888), "In 1991-92, a random, nationwide sample of 100,000 Norwegian women born 1943-57 were drawn from the National Register and invited to participate in the Norwegian Women and Cancer Study (NOWAC). A total of 61,000 women were randomly sampled in 1991, and an additional 39,000 (Norwegian citizens only) in 1992. The women received a mailed letter of invitation requesting informed consent and a self-instructive questionnaire." Later (p. 889): "Of the 100,000 women initially invited to participate in NOWAC, 6000 were given a questionnaire without dietary questions. The responders of this questionnaire (n = 3,694) were not included in the present analyses." I'm at a loss to understand how a potentially biased group of researchers could have used this to their advantage, e.g. how they could have known in advance that the dietary habits of these virtually anonymous 6000 women would later correlate with first cases of breast cancer in a way that would incriminate milk. If I'm missing something here, please spell it out. <<As Hjartåker (whom I asked for comment) explains: "Cohort studies [studies that follow a clearly defined group of people over time] always only include subjects that are free from the disease under investigation. In our situation, free from cancer.">> That reveals the flaw. Hjartaker clearly set up the parameter of the study. She defined the terms. Does milk consumption as a child cause cancer as an adult? This question cannot be answered honestly by eliminating those who got cancer. cancer? ***Again, a prospective cohort study, which is one of a handful of standard research designs for studying people and disease, BY DEFINITION must not include subjects who already have (or may recently have had) the disease being investigated (or who have ANY serious disease in hypercautious cohort studies). This is standard textbook stuff - not some arbitrary or biased decision by Hjartaker who would have shown professional incompetence if she had designed the study otherwise, as you suggest she should have. The idea of a prospective design is to start with a blank slate, "no baggage." Also, please note that Hjartaker's study was a "study within a study" (like so many other such studies based on The Nurses' Health Study, the Honolulu Heart Program, the Framingham Study, etc.), in this case the NOWAC study which was formulated to look for causes of ALL types of cancer in women by comparing baseline dietary and other characteristics in women who went on to get cancer and those who didn't. This is why women with any type of cancer who responded to the invitation to join the study in 1991-92 were told, "sorry, no thanks." Rightly or wrongly, scientists believe that if you already have a disease like breast cancer, simply knowing that could bias your recollection or perception of the very dietary and other lifestyle factors under study. For example, you might well think "I got this because I drank too much milk"; and that suspicion could lead you to overestimate how much milk you actually drank. Or, knowing that you have breast cancer, you might have changed your milk-drinking habits ("from now on, no cow hormones for me, thank you very much"). If you were included in a prospective study of this kind which asks (to quote from the paper) about your "adult milk consumption at baseline" (i.e. when you received the questionnaire), you would report a low consumption, but it would have been as a RESULT of your diagnosis of breast cancer not as a cause. <<Indeed, the study was essentially a fishing expedition to take the measure (dietary and otherwise) of a very large, randomly selected "cohort" of cancer-free premenopausal women at its inception in 1991 and 1992, and, as the years go by, to see how those measurements relate to who gets cancer and who doesn't.>> Indeed????? Essentially??? They were not randomly selected if a large part of the population was excused for having cancer which they may have gotten as a result of childhood milk consumption. ****Or, if one approaches this question without bias, who may have gotten cancer as a result of having drunk relatively LESS milk in childhood. There was no way for the researchers to know the answer to that question in advance. Instead of trying to answer it by means of a comparatively bias- and error-prone case-cohort design - which would have allowed the inclusion of the women with breast cancer at the outset - the researchers opted to investigate the possible links between childhood and adulthood diet (milk was just one of many items on the dietary questionnaire) and breast cancer through a LESS biased study design: a prospective cohort study. As you know, researchers have limited budgets. It would have been interesting to have seen what a case-cohort study would have shown; but one can hardly fault the researchers for piling their pennies into a more objective prospective study instead. <<When I emailed Hjartåker for her two cents worth, she agreed that "Cohen must have made a gross and arbitrary exaggeration of the proportion of women in the low milk intake group.">> ASK HER HOW SHE DETERMINED LOW, MEDIUM, AND HIGH CONSUMPTION. The numbers are different for kids and adults. How did she draw her arbitrary lines. Is low consumption 1-2 glasses or less than one, etc. <<Walsh steered me to a few lines in the "methods" section I had bumblingly overlooked wherein Hjartåker and company do explain their formula. It is a bit of a braintwister, which might explain Cohen's incomprehensible interpretation. To quote from the paper:>> ****The explanation, as I reprinted from Hjartaker's paper itself and explained in the draft I sent to you, makes it very clear how they created these groups. If there's something about their method that you think could have biased their results, please explain. Incomprehensible intermpretation? Perhaps we should not do the interview, and have you just write whatver you will. ****That's entirely up to you if you feel you have nothing more to add to explain how you arrived at your interpretations, calculations, and conclusions, particularly this one: . . . the expectatiopn [sic] of breast cancers for low milk consuming females was 156 cases out of 311. The actual number of cases was only 42. The expected number of cases of breast cancer for the moderate and high milk consumption group was 155 cases. The actual number of cases of breast cancer for the milk drinkers was 269. In other words, the authors mis-read [sic] their own data. Women who drank a lot of milk as children developed more cases of breast cancer than notmilk users. How much more? A factor of 640%! ****Please let me know if you'd still like to speak to me on April 23, as scheduled. Otherwise, I'd be happy to reprint this exchange as an appendix to my article and let readers decide for themselves where the bias lies. *****In the interest of being thorough, let me also reply to your other message here. You wrote: In any study, criteria must remain standardized. Let me ask you this. In th AH study, please define: CHILDREN Low milk consumption - How much? Medium consumption - How much? High consumption - How much? ADULT Low milk consumption - How much? Medium consumption - How much? High consumption - How much? Thanks, Robert ****As you know, the questionnaire gave the women a four part multiple choice answer for the two separate questions about their childhood and adulthood levels of milk consumption, respectively. As you should also know, having read this paper so critically, the researchers write that "Based on wholesale statistics, we know that the per capita consumption of milk in Norway in the 1950s, when the women were growing up, was high." Acc0rdingly, the multiple choice for childhood milk consumption was set at higher levels than for adult milk consumption, but both included "none" as the bottom level, and 7 or more glasses a day as the highest level for childhood and more than 3 glasses a day as the highest level for adulthood. I don't see any room for an anti-milk bias in this decision, which also seems like a reasonable accomodation to the fact that children tend to drink more milk so they can "grow up and be strong" than adults. ****If you can provide a credible argument as to how this lack of standardization between the multiple choices for childhood and adulthood milk consumption might have introduced significant bias FOR MILK into the study, I'm all ears. Regards, Syd Baumel ______________________________________________________ Subject: LET'S TRY THIS AGAIN, SYD From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Wed, 17 Apr 2002 21:14:52 -0400 To: "baumel@mts.net" <baumel@mts.net> Dear Syd, Perhaps you do better with "fill in the blanks" CHILDREN Low milk consumption - How much? ______ Medium consumption - How much? ______ High consumption - How much? ______ ADULT Low milk consumption - How much? ______ Medium consumption - How much? ______ High consumption - How much? ______ Are you capable of keeping this simple? ;>) Thanks, Robert ______________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: LET'S TRY THIS AGAIN, SYD Date: Thu, 18 Apr 2002 01:11:07 -0500 ----- Original Message ----- From: <i4crob@earthlink.net> To: <baumel@mts.net> Sent: Wednesday, April 17, 2002 8:14 PM Subject: LET'S TRY THIS AGAIN, SYD
Dear Syd, Perhaps you do better with "fill in the blanks" CHILDREN Low milk consumption - How much? ______ Medium consumption - How much? ______ High consumption - How much? ______ ADULT Low milk consumption - How much? ______ Medium consumption - How much? ______ High consumption - How much? ______ Are you capable of keeping this simple? ;>) ****Robert, I'm keeping it as simple as I can without being inaccurately simplistic. I've gone to a lot of trouble to explain myself as clearly and thoroughly as I can. If there's anything I've written that you don't understand, please say so, and I'll try again. ***To answer your question: As someone who has read the original paper and (I hope!) my previous emails, you should know that the questionnaire didn't ask about "low," "moderate," or "high" consumption, but about four quantitatively defined levels of consumption (childhood [glasses per day]: none, 1-3, 4-6, 7 or more; adulthood: none, 0.1-1.0, 1.1-3.0, 3.1 or more). So the blanks in your question can't be filled - unless you would like to fold two categories into one and reclassify the remaining three as low, moderate, and high. Is there any way you believe that would make this a better study? ***Perhaps you're hinting at the question of how to reclassify in an unbiased way the women into three "low," "moderate," and "high" groups that meaningfully combine their childhood AND adulthood (at entry into the study) milk consumption. Hjartaker et al. chose to do it in a way that strikes me as an elegant solution to the problem. Can you think of any other way(s) that might have yielded a significantly different result, in particular a result that would have been statistically insignificant or significantly AGAINST milk? ***I hope I've answered your question. I'd still like to know how you arrived at the risk ratio figures you published in your critique, because this, of course, is key to understanding your contention that a serious fraud has been committed by the researchers. Failing that explanation, I have to go with what I've got, based on my own careful reading of the paper and consultation with Stephen Walsh and Anette Hjartaker. So again, please explain yourself and show me the error of my ways or admit that you were wrong. ***Regards, ***Syd Thanks, Robert _______________________________________________ Subject: FINAL ATTEMPT From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Thu, 18 Apr 2002 05:20:09 -0400 To: "baumel@mts.net" <baumel@mts.net> CC: "notmilk@earthlink.net" <notmilk@earthlink.net> FINAL ATTEMPT Dear Syd, You are trying to play a ball game with me (in the big leagues) and cannot even get to first base (YOU NEVER PLAYED LITTLE LEAGUE BALL, DID YOU?) You do not seem capable of answering even the simplest question without providing a long rambling statement. This is my final request. Failure to respond to this most basic question will terminate our EMAIL communication, and end our interview. PLEASE FILL IN THE BLANKS: CHILDREN Low milk consumption - How much? ______ Medium consumption - How much? ______ High consumption - How much? ______ ADULT Low milk consumption - How much? ______ Medium consumption - How much? ______ High consumption - How much? ______ Robert Cohen (Lisa--please file this. It's clear that I am being set up, and this so-called reporter and his journal may very well be hit with a libel and slander suit similar to the brief we are preparing for the JN/ES thing. As per the other EMAILS, this needs to be well documented--Robert) suit ________________________________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: FINAL ATTEMPT Date: Thu, 18 Apr 2002 04:41:40 -0500 Robert, You're right about one thing: I'm not in the same "big league" as you. Thank God. I have no idea how to play whatever game it is you think you're playing or how to answer your riddle. I'm happy to join you in terminating this fruitless correspondence. Happy litigating. If you want to sue, sue me personally. Syd Baumel __________________________________ Subject: FINAL ATTEMPT From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Thu, 18 Apr 2002 05:50:15 -0400 To: "baumel@mts.net" <baumel@mts.net> CC: "notmilk@earthlink.net" <notmilk@earthlink.net> You're right about one thing: I'm not in the same "big league" as you. Thank God. Your REFUSAL to answer my repeated request reveals your intentions, Syd. I suspect that you tried, and in doing so rervealed the basic flaw of this study. Now that you are armed with truth, I expect you to write it. Failure to do so will respond in legal action against you and your journal. As you know, I have taken a lot of crap, and will accept no more. Should you wish to continue this discussion, you must first respond to my SIMPLE question. I suspect that you will not. If that is the case, you are a pathetic excuse for a journalist. Robert Cohen ______________________________ From: "Syd Baumel" <baumel@mts.net> To: <i4crob@earthlink.net> Subject: Re: FINAL ATTEMPT Date: Thu, 18 Apr 2002 12:30:14 -0500 Robert, I can't reveal something I don't know and that you refuse to tell me. For the last time, explain yourself (as I have), or forever hold your peace (such as it is). Syd (Anna: Please archive these messages, because, as you know, I know how to write emails, but not how to store them and I have a nervous tic that causes me to type whatever I'm saying to you into my emails to other people. Also please see about that adjustment to my meds.) _________________________________________ Subject: FINAL ATTEMPT From: "i4crob@earthlink.net" <i4crob@earthlink.net> Date: Thu, 18 Apr 2002 15:59:11 -0400 To: "baumel@mts.net" <baumel@mts.net> I can't reveal something I don't know and that you refuse to tell me. Brush on, brush off, brush on, brush off, brush on, brush off. The information you seek is before you. Unless you discover the secret, you will not experience truth. Read the AH study and fill in the blanks. Your refusal to do so is perplexing.
For more on the controversy over milk see "Milk: What is the Deal" at www.aquarianonline.com/Wellness/Milk.html Copyright © 2002 by Syd
Baumel.
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